Measure the nuclei you need for your experiment with the world’s first broadband benchtop NMR spectrometer.
New shimming technology allows spectral resolution of <0.35Hz/10Hz as standard.
No requirement for special facilities or liquid cryogens allowing you to use the instrument wherever is most convenient.
Removable and easy-to-access probe for cleaning. Use with standard 5mm NMR tubes or easy-to-use flow cell.
Interchangeable X-Pods allow you to optimise signal-to-noise ratio for specific nuclei.
Quick Experiments turn complex pulse sequences into a single click allowing anyone to access the power of NMR.
SpinFlow advanced mode allows you to define your own experiments, your way.
Flow liquid samples at variable temperature (20°C – 70°C) without spectral artefacts. Run high duty cycle pulse sequences without destabilising the magnet.
True broadband capability gives you the freedom to select the nuclei you need for your experiments, whether 1H, 13C, 31P, or something more exotic like 29Si, 11B, or 7Li. Just choose the nucleus of interest in the software and adjust the probe to ensure you are operating under the optimum conditions.
Maximising the signal-to-noise ratio for some benchtop NMR experiments can be the difference between success and failure. For those nuclei with low receptivity, such as 13C or 31P, ensuring sensitivity is paramount. The interchangeable X-Pods of the X-Pulse give you the added flexibility to achieve maximum signal-to-noise ratio for specific nuclei. These pods can be exchanged quickly and easily without shutting down the system. This allows you to be up and running with either maximised sensitivity or the flexibility of multinuclear spectroscopy whenever you need it.
Due to inherent limitations in spectral line separation, it is not easy to study polymers using 1H NMR spectroscopy. Wide, overlapping lines make the analysis of spectra difficult. We investigated the use of 13C NMR spectroscopy as an alternative for identifying types of nylon in industrial nylon-based products. All measurements were performed on an X-Pulse at 37°C. The concentration of the polymer solution was approximately 5% by weight. 13C NMR spectra were acquired for three reference nylon samples (nylon 6, 66, 612). A simple comparison with the reference spectra allowed the identification of the type of nylon in the products. For example, the white cable tie is made of nylon 66 and the fishing line is nylon 6.
This is the 1H NMR spectrum of a solution of an industrial polymer material. The sample was taken from a product batch containing 0.15% by weight of an antioxidant agent. (Reference value provided by manufacturer.) The material concentration in the solution was approximately 1% by weight.
Analysis of the NMR spectrum allowed an estimation of the antioxidant concentration using the TMS signal as an internal reference. The antioxidant content was estimated at 0.16% by weight, matching the manufacturer’s reference value.
With X-Pulse your NMR peaks are easier to separate and lower concentrations become visible. X-Pulse uses a 60MHz (1.4T) permanent magnet.
New shimming technology in X-Pulse allows us to generate an extremely homogeneous field, delivering resolution of less than 0.35Hz at the half-height and lineshape of 10Hz at 0.55%.
Peaks are easier to identify but also combined with shaped RF pulses solvent suppression is much more effective allowing even challenging compounds such as sugars and starches dissolved in water to be analysed.
Shaped pulses open up a large array of advanced pulse sequences to improve the understanding of your samples. Improved solvent suppression allows you to see peaks that would have previously been hidden. Selective experiments such as 1D-TOCSYs allow you to excite specific parts of molecule, enabling you to identify and distinguish separate compounds in complex mixtures.
The X-Pulse flow cell allows you to flow liquid samples at variable temperature (20°C – 70°C) so that you can learn more about your reactions. The flow cell is optimised to allow as large a sample volume as possible to flow through the probe to be measured. This minimises measurement time for each spectrum and allows better understanding of the time dependence of reactions. Designed with flexibility in mind, the flow cell also allows you to choose your external lock solvent, ensuring that you avoid unnecessary spectral overlaps or having to dope your reaction mixture. The variable temperature probe ensures that you are able to measure your chemistry in its optimum conditions either to maintain the reaction, or to vary temperature to understand specific reaction dynamics. The variable temperature probe can also be used without the flow cell to maintain a specific sample state, or to stop your sample heating during high duty cycle experiments.
The unique magnet design of X-Pulse delivers extremely high stability, ensuring that your experiments are artefact-free.
The large thermal mass of the magnet ensures that whether you are flowing liquids at 20°C or 70°C through your flow cell, you can collect stable artefact-free data.
The thermal and magnetic shielding of the system minimises the effect of the environment, ensuring that variations in room temperature or local electromagnetic fields do not affect your data.
X-Pulse is the only benchtop NMR system with a user-removable probe, making cleanup quick and easy. If a sample accidentally spills or an NMR tube breaks, there is no need to call service or to tip over the instrument – just pull out the probe and clean straight through. Even better, X-Pulse sample tubes are inserted directly into the instrument – no fussing with a spinner, sample holder, or depth gauge – significantly reducing the chance of breakage and increasing your throughput.
X-Pulse also means no more cryogen fills and no more worries about quenching the magnet. Just plug X-Pulse into a standard mains outlet and forget about cryogen supplies and costs.
The magnetic field used by X-Pulse to perform NMR spectroscopy is produced by a permanent magnet. There is no need for cryogens to cool the system, significantly reducing running costs.
The benchtop footprint and minimal stray field allow X-Pulse to be installed in a wide range of environments without the need for special facilities. You can perform NMR right next to your experiments in your when lab, or even next to your process reactor allowing you to easily better understand your reaction processes.
In addition, the optional X-Pulse trolley gives you the ability to easily move the system where you need to.
X-Pulse provides high quality 1D and 2D NMR spectra of 1H, 19F, 13C, 31P, 29Si, 11B and other nuclei. A library of pulse sequences including 1D, COSY, DEPT, HSQC, ME-HSQC, HMBC and many others is standard with every system so everything is ready to go.
2D 1H -13C ME-HSQC
2D 1H-13C HMBC
2D 1H COSY
2D J-Resolved Spectrum
2D 1H TOCSY
13C 1D Edited DEPT
29Si 1D NMR Spectrum
11B 1D NMR Spectrum
31P 1D NMR Spectrum
19F 1D NMR Spectrum
Our new SpinFlow software brings a new level of ease-of-use to X-Pulse. Predefined “quick" experiments allow you to collect routine data such as a basic 1D 1H spectrum or even a 13C DEPT with a single click. New user-defined experiments allow experienced users to save their own sequences and parameters to be run again later, ensuring consistency while decreasing the time it takes to collect your data.
SpinFlow offers more than "quick" experiments for routine use. Advanced experiments allow you to customise every parameter in a sequence to optimise it precisely for your experiment. If the standard SpinFlow pulse sequences do not cover your particular experiment, then you can easily create your own using simple Python scripts.