Quantifying the active pharmaceutical ingredient (API) is essential in drug development, manufacturing, and quality control / quality assurance. Quantitative NMR spectroscopy is a primary method for quantifying APIs.
Lansoprazole is used to treat gastroesophageal reflux; and is used as an example to show how a small drug molecule can by characterised and quantified by one-dimensional proton and carbon-13 NMR, along with COSY, HSQC & HMBC two dimensional spectra on the X-Pulse Broadband Benchtop NMR Spectrometer.

Download the application note to learn:

• How to characterise small organic molecules by one- and two-dimensional NMR spectroscopy
  
• The importance of accurately quantifying active pharmaceutical ingredients (APIs)
• How to accurately quantify signals in NMR spectra

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